Acivir is an antiviral medication effective against:

• Herpes simplex virus (HSV) infections of skin and mucous membranes
• Herpes zoster (shingles) infections
• Initial and recurrent genital herpes outbreaks
• Varicella (chickenpox) infections
• Prophylaxis and treatment in immunocompromised patients (including HIV/AIDS)
• Post-bone marrow transplantation cases

Dosage and Administration

• Begin treatment at first symptom appearance (tingling, blistering)
• Take with a full glass of water; maintain adequate hydration
• May be taken with or without food (food may reduce stomach upset)
• Complete full prescribed course, even if symptoms improve earlier
• For missed doses: take when remembered unless close to next dose
• Keep lesions clean, dry, and protected from irritation

Important Safety Information Contraindications:

• Hypersensitivity to acyclovir or valacyclovir
• Severe renal impairment (requires dose adjustment)

Precautions:

• Renal function monitoring required
• Maintain proper hydration during treatment
• Increased photosensitivity risk (use sun protection)
• Potential for neurological effects (dizziness, drowsiness)
• Does not cure infection or prevent viral transmission

Special Populations

• Elderly: Increased sensitivity to CNS effects
• Pregnancy: Risk-benefit assessment required
• Breastfeeding: Excreted in breast milk - consult physician
• Immunocompromised: May require different dosing regimen

Drug Interactions

• Nephrotoxic agents (increased renal toxicity risk):
• Aminoglycosides
• NSAIDs
• Cyclosporine
• Vancomycin
• Probenecid (may increase acyclovir levels)

Adverse Effects Common:

• Gastrointestinal disturbances
• Headache
• Malaise

Serious (require immediate medical attention):

• Allergic reactions
• Neurological symptoms
• Renal impairment
• Hematological abnormalities
• Severe skin reactions

Storage and Handling

• Store at 20-25°C (68-77°F)
• Protect from moisture and light
• Keep out of reach of children
• Do not store in bathroom

Patient Counseling

• Importance of completing treatment course
• Hydration requirements
• Sun protection measures
• Sexual transmission precautions
• Monitoring for adverse effects
• Proper storage conditions

Note: This medication does not treat common cold or influenza viruses. Consult healthcare provider for complete prescribing information.